Just one dose can cause death in someone using this medicine accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash. Since codeine is used for pain, you are not likely to miss a dose.
Skip any missed dose if it is almost time for your next dose. Do not use two doses at one time. Seek emergency medical attention or call the Poison Help line at A codeine overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose can cause severe muscle weakness, cold and clammy skin, pinpoint pupils, very slow breathing, extreme drowsiness, or coma. Avoid driving or hazardous activity until you know how this medicine will affect you.
Dizziness or drowsiness can cause falls, accidents, or severe injuries. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Opioid medicine can slow or stop your breathing, and death may occur. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. Serious side effects may be more likely in older adults and those who are overweight, malnourished, or debilitated.
Long-term use of opioid medication may affect fertility ability to have children in men or women. It is not known whether opioid effects on fertility are permanent. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may have breathing problems or withdrawal symptoms if you start or stop taking certain other medicines. Tell your doctor if you also use an antibiotic, antifungal medication, heart or blood pressure medication, seizure medication, or medicine to treat HIV or hepatitis C.
Opioid medication can interact with many other drugs and cause dangerous side effects or death. These people are at an increased risk of toxicity caused by the increased amounts of morphine produced.
In Australia, codeine is available over the counter by itself or in combination with a range of other drugs in low-dose formulations 8mg, 15mg such as with the anti-inflammatory drug ibuprofen.
Stronger tablets 30mg are only available by prescription. Its main use is to relieve pain and to treat minor aches, including headaches, but only for a short term. Doctors can prescribe a higher-dose form forte formulations containing 30mg codeine for more significant aches and pains. Low-dose forms are also used to treat coughs antitussive , often available as syrup or linctus. Codeine can also help reduce the effects of nausea and diarrhoea without causing significant side effects. Codeine is the most widely and commonly used prescription opiate in the world.
Health Tools. Brand Names:. Reviewed: June 23, You should not use this medicine if you are allergic to it, or if you have: severe asthma or breathing problems; a blockage in your stomach or intestines; or frequent asthma attacks or hyperventilation. Tell your doctor if you have ever had: liver or kidney disease; breathing problems, sleep apnea; abnormal curvature of the spine that affects breathing; a head injury or brain tumor; low blood pressure; blockage in your digestive tract stomach or intestines ; problems with your gallbladder, pancreas, or thyroid; Addison's disease or other adrenal gland disorder; enlarged prostate, urination problems; or mental illness, drug or alcohol addiction.
Side Effects. Side Effects What are the side effects of Codeine? Call your doctor at once if you have: noisy breathing, sighing, shallow breathing, breathing that stops during sleep; a slow heart rate or weak pulse; a light-headed feeling, like you might pass out; confusion, unusual thoughts or behavior; feelings of extreme happiness or sadness; seizure convulsions ; problems with urination; or low cortisol levels --nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.
Common side effects include: feeling dizzy or drowsy; constipation; or nausea, vomiting, stomach pain. Based on FDA pregnancy categories. Interactions What drugs and food should I avoid while taking Codeine?
Do not drink alcohol. Dangerous side effects or death could occur. Take codeine with food or milk if it upsets your stomach. What should I do if I missed a dose of Codeine?
Overdose Signs What happens if I overdose on Codeine? Blood tests may be needed to check for unwanted effects. Check with your doctor before using this medicine with alcohol or other medicines that affect the central nervous system CNS. The use of alcohol or other medicines that affect the CNS with codeine may worsen the side effects of this medicine, including dizziness, poor concentration, drowsiness, unusual dreams, and trouble with sleeping. Some examples of CNS depressants are antihistamines or medicine for hay fever, allergies, or colds, sedatives, tranquilizers, or sleeping medicines, medicine for depression, medicine for anxiety, prescription pain medicine or narcotics, medicine for attention deficit and hyperactivity disorder, medicine for seizures or barbiturates, muscle relaxants, or anesthetics numbing medicines , including some dental anesthetics.
This effect may last for a few days after you stop taking this medicine. This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions. If you think you or someone else may have taken an overdose of this medicine, get emergency help at once. Your doctor may also give naloxone to treat an overdose. Signs of an overdose include: cold, clammy skin, coughing that sometimes produces a pink frothy sputum, dark urine, difficult or trouble breathing, irregular, fast or slow, or shallow breathing, nausea or vomiting, pain in the upper stomach, pale or blue lips, fingernails, or skin, pinpoint pupils of the eyes, or yellow eyes or skin.
This medicine may cause sleep-related breathing problems eg, sleep apnea, sleep-related hypoxemia. Your doctor may decrease your dose if you have sleep apnea stop breathing for short periods during sleep while using this medicine. Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position.
Getting up slowly may help. Also, lying down for a while may relieve dizziness or lightheadedness. If this problem continues or gets worse, check with your doctor right away. This medicine may make you dizzy, drowsy, confused, or disoriented. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
Using narcotics for a long time can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems. Do not change your dose or suddenly stop using this medicine without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely.
This may help prevent worsening of your condition and reduce the possibility of withdrawal symptoms, including anxiety, fever, nausea, runny nose, stomach cramps, sweating, tremors, or trouble with sleeping. Using this medicine while you are pregnant may cause serious unwanted effects, including neonatal withdrawal syndrome in your newborn baby.
Tell your doctor right away if you think you are pregnant or if you plan to become pregnant while using this medicine. Codeine is changed to morphine in the body. Some people change codeine to morphine more quickly than others. These individuals are called "ultra-rapid metabolizers of codeine".
Contact your doctor immediately if you experience extreme sleepiness, confusion, or shallow breathing. These symptoms may indicate that you are an "ultra-rapid metabolizer of codeine".
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