Select personalised content. Create a personalised content profile. Measure ad performance. Select basic ads. Create a personalised ads profile. Select personalised ads. Apply market research to generate audience insights. Measure content performance. Develop and improve products. List of Partners vendors. Wellbutrin bupropion is an antidepressant that treats a number of conditions. It comes as an immediate-release, sustained-release, or extended-release tablet that is taken orally.
One factor that makes Wellbutrin especially unique among antidepressants is that it doesn't tend to affect your libido and sexual function. In fact, it's often prescribed along with other antidepressants to help counter the sexual side effects , like loss of desire, found in other types.
Additionally, another brand of bupropion the active ingredient in Wellbutrin called Zyban is used to help people quit smoking. Other off-label uses sometimes include treatment for social anxiety disorder, post-traumatic stress disorder PTSD , and even some forms of nerve pain.
Your doctor will evaluate your symptoms and current health status to determine if Wellbutrin is right for you. Your doctor may not prescribe this drug if you have certain health conditions. It's not clear whether Wellbutrin is safe to take during pregnancy. In animal studies, there has been some evidence of adverse effects on the fetus, but we don't yet have enough data about its effect on humans. The potential benefits of continuing Wellbutrin during pregnancy may outweigh the possible risks, but this should be discussed closely with your doctor.
Wellbutrin can be present in breastmilk, so caution should be used by people who are breastfeeding. If you are lactating, your doctor can help you weigh your options. Because older adults may have reduced kidney function, they may require smaller doses since the drug remains in the body longer.
Adverse events related to drug therapy, however, may start immediately. If side effects are too bothersome, patients may be tempted to discontinue therapy before realizing the full benefit. Zoloft is much more likely than Wellbutrin to cause nausea and vomiting.
This can affect daily activities and functioning. Somnolence, or excessive drowsiness, is also much more common with Zoloft. This can affect productivity and safety and may be an important consideration for patients and providers. Wellbutrin is not known to cause sexual dysfunction or decreased libido like SSRIs such as Zoloft can.
This is an important effect to discuss with patients prior to starting therapy. The following list is not intended to be a complete list of adverse events. Please consult a pharmacist, doctor, or another medical professional for a complete list of possible side effects.
Wellbutrin and Zoloft each have multiple possible drug interactions primarily due to their metabolism by the cytochrome P system. Examples of CYP2D6 substrates include codeine, haloperidol, risperidone, and metoprolol. Zoloft is a minor inhibitor of CYP2D6 and may cause the same interactions but to a lesser degree.
Other drugs with serotonergic actions when combined with Zoloft may increase the risk for serotonin syndrome. Serotonin syndrome is the result of abnormally high levels of free serotonin and can result in agitation, dizziness, and increased heart rate. Zoloft may cause a specific type of cardiac arrhythmia known as a prolonged QTc interval when taken with certain classes of medication.
It is important that your healthcare professional and pharmacist have a complete list of medications you are taking in order to appropriately screen for potential interactions. The following list is not intended to be a complete list of drug interactions. Your doctor or pharmacist can provide a complete list. Wellbutrin and Zoloft therapy may increase suicidal ideation and thoughts among teens and young adults, especially in the early stages of treatment before any type of remission is achieved.
These patients must be monitored closely if this treatment is deemed medically necessary. A therapy change may be necessary if symptoms suddenly arise or get worse. All patients with depression may experience a worsening of their depression or suicidal thoughts whether or not they are taking antidepressant medications.
Some patients who take Wellbutrin for smoking cessation, and who have no previous history of depression, may experience mental changes when they begin therapy. These changes may include mood changes, hallucinations, paranoia, delusions, aggression, and anxiety. Speak with your healthcare provider immediately if any of these changes occur when you initiate Wellbutrin therapy.
Wellbutrin has been shown to increase the risk of seizure, and for this reason, the total daily dose should not exceed mg.
Patients on Wellbutrin may also experience increased blood pressure, leading to hypertension, even if they had no previous cardiovascular conditions or events.
Depression symptoms will not start to resolve immediately with either Wellbutrin or Zoloft. Typically, changes in symptoms take a minimum of two weeks to observe, with most patients needing at least four to six weeks to see if the drug is having an impact on their symptoms.
This can be brought on by the use of two serotonergic drugs together. Symptoms may include agitation, dizziness, or palpitations. This study also sought to compare the prevalence of negative sexual side effects. The results found that Wellbutrin and Lexapro produced similar improvements in depressive symptoms, however, Wellbutrin was significantly less likely to cause sexual dysfunction.
Wellbutrin and Lexapro affect different neurotransmitters and are oftentimes used together. The results of one clinical trial found that the use of both drugs together leads to significantly higher response and symptom remission rates as compared to typical monotherapy with SSRIs.
While further studies may be warranted, this study suggests some value in dual therapy with both medications. Sign up for Wellbutrin price alerts and find out when the price changes! Wellbutrin is a prescription medication that is typically covered by both commercial and Medicare drug plans.
Lexapro is also a prescription medication that is typically covered by both commercial and Medicare drug plans. Try the SingleCare prescription discount card. Wellbutrin and Lexapro affect the levels of different neurotransmitters. While their potential to cause certain side effects may be similar, there are some key differences.
Lexapro, like other SSRIs, has the potential to cause decreased libido or sex drive. Wellbutrin had no reported incidence of decreased libido. Wellbutrin causes headache in as much as a quarter of the patients who take it, while headaches were not reported with Lexapro. Wellbutrin and Lexapro both may cause nausea, vomiting, sweating, and diarrhea.
The following list is not intended to be a complete list of adverse events. Please consult a pharmacist, doctor, or another medical professional for a complete list of possible side effects. If co-administration of Wellbutrin and a CYP2D6 substrate is needed, it may be necessary to decrease the dose of the 2D6 substrate. Some examples of CYP2D6 substrates include fluoxetine, sertraline, haloperidol, risperidone, and metoprolol.
The use of Lexapro with tricyclic antidepressants, such as amitriptyline, may increase the risk of QT prolongation and serotonin syndrome. In general, this combination should be avoided. The following list is not intended to be a complete list of drug interactions. It is best to consult your provider or pharmacist for a complete list. Patients with MDD may experience a worsening of depression or suicidal thoughts whether or not they are taking antidepressant medications.
These conditions may worsen until remission is achieved. Wellbutrin and Lexapro therapy may increase suicidal ideation and thoughts among teens and young adults, especially in the early stages of treatment before any type of remission is achieved.
These patients must be monitored closely if this treatment is deemed medically necessary. A therapy change may be necessary if symptoms suddenly arise or get worse. Patients taking bupropion products for smoking cessation and who have no previous history of depression, may experience mental changes when they initiate therapy.
These can include mood changes, hallucinations, paranoia, delusions, aggression, and anxiety. If this occurs, speak with your healthcare provider immediately.
In the case of both Wellbutrin and Lexapro, depression symptoms do not start to resolve immediately. Wellbutrin should not be taken within 2 weeks of stopping MAOIs. When used to help people stop smoking, bupropion is sold as Zyban or Chantix. The Food and Drug Administration FDA warns that people who are taking one of these drugs to stop smoking must not take the same drug under another name to treat depression.
This will increase the dose of the same ingredients, and it may raise the risk of seizures. Ritonavir or efavirenz are used to treat HIV infection. These can reduce the effects of Wellbutrin. People with liver problems should discuss with their doctor whether or not Wellbutrin is suitable, before taking it.
A severe allergic reaction known as anaphylaxis can occur if a person has an allergy to any of the ingredients in Wellbutrin. If any of the following symptoms occur, medical assistance should be sought immediately: a skin rash, itching, trouble breathing, chest pain, or swelling of the face, tongue, or throat.
Alcohol : This should be avoided or at least severely limited when using Wellbutrin, as it has been linked to neuropsychotic side effects in a few cases. Pregnancy and breastfeeding : Mouse studies have not shown that Wellbutrin is likely to harm a pregnancy or the developing fetus.
However, since drugs do not alway affect humans and animals in the same way, this drug should only be used in pregnancy and breast feeding if it cannot be avoided. Bipolar disorder : A major depressive episode can develop into the first signs of bipolar disorder.
A doctor should monitor the patient for signs of this. Wellbutrin is not approved for use in bipolar disorder. Driving and use of machinery : Dizziness, tiredness, blurred vision, and a false sense of wellbeing can occur when using this drug. Because of this, using heavy machinery or driving should be considered with caution. Overdose : In rare cases, an overdose has led to seizures.
Anyone who may have taken an overdose should go to the hospital.
0コメント